Principal Investigator

Alexis Komor, Ph.D.

Assistant Professor

Office: 4120D Urey Hall, UCSD
Email: akomor at ucsd.edu

Alexis received her B.S. degree in chemistry from the University of California, Berkeley in December of 2008. While at Berkeley, she conducted research under the guidance of Professor Christopher J. Chang on the design of first-row transition metal catalysts for dioxygen activation and group transfer for three years. She then joined the lab of Jacqueline K. Barton at the California Institute of Technology for her doctoral studies. While at Caltech, she worked as an NSF Graduate Research Fellow on the design, synthesis, and study of DNA mismatch-binding metal complexes and received her Ph.D. in 2014. She pursued postdoctoral work as a Ruth L. Kirschstein NIH Postdoctoral Fellow in the laboratory of David R. Liu, where she developed base editing, a new approach to genome editing that enables the direct, irreversible chemical conversion of one target DNA base into another in a programmable manner, without requiring double-stranded DNA backbone cleavage. Alexis joined the Department of Chemistry and Biochemistry at the University of California at San Diego in the fall of 2017.

Assistant Professor, University of California, San Diego
(2017-present)
Post-doctoral Fellow, The Broad Institute of MIT and Harvard
(2014-2017)
Ph.D. in Chemistry, California Institute of Technology
(2009-2014)
B.S. in Chemistry, University of California, Berkeley
(2005-2008)

Alexis' CV

Post-Doctoral Scholars

Zsolt Bodai, Ph.D.

zbodai at ucsd.edu
Post-doctoral Scholar, Year 1
Post-doc. in Zoltan Takats Lab, Imperial College London
Ph.D. in Analytical Chemistry, Eötvös Loránd University, Budapest
M.S. in Analytical Chemistry, Eötvös Loránd University, Budapest
B.S. in Chemistry, Eötvös Loránd University, Budapest

Graduate Students

Mallory Evanoff

mevanoff at ucsd.edu
Ph.D. student, Year 3
Chemical Biology Track
M.S. in Chemistry, University of California, San Diego
B.S. in Chemistry (Chemical Biology focus), Carnegie Mellon University

Sifeng Gu

gsifeng at ucsd.edu
Ph.D. student, Year 3
Chemical Biology Track
M.S. in Chemistry, University of Edinburgh
B.S. in Environmental Science, South China University of Technology

Elizabeth Porto

eporto at ucsd.edu
Ph.D. student, Year 3
Biochemistry & Biophysics Track
M.S. in Chemistry, University of California, San Diego
B.S. in Biology, University of Missouri-Kansas City
B.S. in Chemistry, University of Missouri-Kansas City

Kartik Rallapalli

krallapa at ucsd.edu
Ph.D. student, Year 3
(Joint student w/ Paesani Lab)
Theoretical & Computational Chemistry Track
M.S. Chemistry, Indian Institute of Technology, Delhi
B.S. Chemistry, Miranda House, University of Delhi

Brodie Ranzau

branzau at ucsd.edu
Ph.D. student, Year 3
Biochemistry & Biophysics Track
M.S. in Chemistry, University of California, San Diego
B.S. in Biochemistry & Molecular Biology, Otterbein University

Quinn Cowan

qcowan at ucsd.edu
Ph.D. student, Year 2
Biochemistry & Biophysics Track
B.S. in Biochemistry, University of Southern California

Carlos A. Vasquez

c5vasque at ucsd.edu
Ph.D. student, Year 2
Chemical Biology Track
B.S. in Chemistry, University of California, Irvine

Ashley T. Wong

ashleytess at ucsd.edu
Ph.D. student, Year 2
Biochemistry & Biophysics Track
B.S. in Biomolecular Engineering & Bioinformatics, University of California, Santa Cruz

Cameron Burnett

cbburnet at ucsd.edu
Ph.D. student, Year 1
Biochemistry & Biophysics Track
M.S. in Chemistry, University of California, San Diego
B.S. in Biochemistry, Boston College

Lab Support

Andrew Wang, Ph.D.

Ph.D. in Chemistry, California Institute of Technology
B.S. in Chemical Biology, University of California, Berkeley

Tango (left) & Cash (right)

Parents: Alexis Komor, Ph.D. & Andrew Wang, Ph.D.

Ukki

Parent: Ashley T. Wong

Nut

Parents: Mallory Evanoff & Maya Holay

Lab Alumni

Maya Parish – Undergraduate
Keolu Fox, Ph.D. – Postdoctoral Scholar – Assistant Professor at UCSD (Anthropology)